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• First line antibiotic therapy is Amoxicillin 8090 mg/kg/day PO divided two times a day for 1014 days Max daily dose is 750 mg to 15 grams/day • Up to 4 weeks of purulent nasal drainage accompanied by nasal obstruction, facial painpressurefullness, or both24 ANTIBIOTIC DOSES Antibiotic Type of infection Dose Method of administration Length of treatment Comments Neonatal meningitis Amoxicillin Age 03 months >1 month 1 < 7 days 100mg/kg 12 hourly 728 days 100mg/kg 8 hourly 00mg/kg 6 hourly Avail oral preparations Slow IV infusion over 30 minutes 21 days 250mg capsules4/05/21 · Treatment With Antibiotics There are some circumstances in which antibiotics work to eliminate sinus infections, such as by fighting bacterial sources But when a sinus infection is caused by allergies, a virus, or other causes such as a structural defect of the sinuses, an antibiotic will not help to alleviate symptoms Http Www Just Edu Jo Dic Clinicguidlines Acute sinusitis and rhinosinusitis Pdf Sinusitis